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Brain Mechanisms Driving Vocal Tics: A Model of Tourette Syndrome

For more details, see the paper by McCairn et al., Neuron 89(2), at http://www.cell.com/neuron/fulltext/S.... Dr. Kevin W. McCairn and colleagues describe their latest findings on how various regions of the brain (basal ganglia and cortex) interact to produce different subtypes of tics (motor vs. vocal). They demonstrate that vocal tics are a consequence of abnormalities in the limbic system and emerge as a consequence of increased alpha (7–12 Hz) phase coupling between nucleus accumbens and anterior cingulate cortex.