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00:00 - Introdução 01:32 - O que é medicina ortomolecular? 07:13 - Doenças causadas por deficiências de vitaminas #medicinaortomolecular #medicinaalternativa #vitaminas Roteiro base: Mateus Freitas Roteiro final: Laura Marise Produção: Laura Marise Edição: Laís Maurelli Design da miniatura: Andre Charneski Legendas: Beatriz Pinheiro Busca de conteúdos: www.nv1c.com Referências: Rees L, Weil A. Integrated medicine. BMJ 2001. doi:10.1136/bmj.322.7279.119 What is Orthomolecular Medicine? x.gd/XpHjj Pauling, L. Orthomolecular psychiatry. Varying the concentrations of substances normally present in the human body may control mental disease. Science 1968 doi:10.1126/science.160.3825.265. Kiani AK, et al. Main nutritional deficiencies. J Prev Med Hyg 2022. doi:10.15167/2421-4248/jpmh2022.63.2S3.2752. Vitamin A and Carotenoids x.gd/z6mM2 Vitamin C x.gd/IlLEZ Vitamin D x.gd/3tb4I RDC 269 de 22/09/2005 x.gd/kNSpP Nutrient Recommendations and Databases x.gd/qtllJ DRI Calculator for Healthcare Professionals x.gd/WTjxo Verly Junior E, et al. Evolution of energy and nutrient intake in Brazil between 2008-2009 and 2017-2018. Rev Saude Publica 2021. doi:10.11606/s1518-8787.2021055003343. Is niacin a possible successful treatment for schizophrenia? x.gd/ruTEL Bjelakovic G, et al. Effects of primary or secondary prevention with vitamin A supplementation on clinically important outcomes: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis. BMJ Open. 2024. doi: 10.1136/bmjopen-2023-078053. ]- Suplementos alimentares. ANVISA. x.gd/LHpND Overview of Vitamins. MSD Manuals, Professional Version. x.gd/OZiMJ Vitamina A Bhattacharya S, Singh A. Phasing out of the Universal Mega Dose of Vitamin-A Prophylaxis to Avoid Toxicity. AIMS Public Health 2017. doi:10.3934/publichealth.2017.1.38. Dewett D, et al. Mechanisms of vitamin A metabolism and deficiency in the mammalian and fly visual system. Dev Biol. 2021. doi: 10.1016/j.ydbio.2021.03.013. Su J, Li T, Pan H. Association of vitamin A supplementation with immune-related allergic diseases: A meta-analysis. Front Nutr. 2022. doi: 10.3389/fnut.2022.984161 Gholizadeh M, et al. Influence of Vitamin A supplementation on inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials. Sci Rep. 2022. doi: 10.1038/s41598-022-23919-x. Bjelakovic G, et al. Effects of primary or secondary prevention with vitamin A supplementation on clinically important outcomes: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis. BMJ Open. 2024. doi: 10.1136/bmjopen-2023-078053. Vitamina C Carr, A.C.; Maggini, S. Vitamin C and Immune Function. Nutrients 2017, 9, doi:10.3390/nu9111211. Cerullo G, et al. The Long History of Vitamin C: From Prevention of the Common Cold to Potential Aid in the Treatment of COVID-19. Front Immunol 2020. doi:10.3389/fimmu.2020.574029. Hemila, H. Vitamin C and Infections. Nutrients 2017. doi:10.3390/nu9040339. Allan GM, Arroll B. Prevention and treatment of the common cold: making sense of the evidence. CMAJ 2014. doi:10.1503/cmaj.121442. Gomez E, et al. Does vitamin C prevent the common cold? Medwave 2018. doi:10.5867/medwave.2018.04.7236. Vorilhon P, et al. Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A meta-analysis in children. Eur J Clin Pharmacol 2019. doi:10.1007/s00228-018-2601-7. Ran L, et al. Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials. Biomed Res Int 2018, 2018. doi:10.1155/2018/1837634. van Gorkom GNY, et al. The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review. Nutrients 2019. doi:10.3390/nu11050977. Zasowska-Nowak A, et al. High-Dose Vitamin C in Advanced-Stage Cancer Patients. Nutrients 2021. doi:10.3390/nu13030735. Roy S, et al. Megadose Vitamin C Prescription Through Alternative Medicine Leading to End-Stage Renal Disease: Case Study and Literature Review. J Investig Med High Impact Case Rep 2023. doi:10.1177/23247096231158954. Vitamina D Thompson B, et al. Vitamin D supplementation and major cardiovascular events: D-Health randomised controlled trial. BMJ 2023. doi:10.1136/bmj-2023-075230. Narvaez J, et al. Vitamin D Megadose: Definition, Efficacy in Bone Metabolism, Risk of Falls and Fractures. Open Access Rheumatol 2020. doi:10.2147/OARRR.S252245. Rizzoli, R. Vitamin D supplementation: upper limit for safety revisited? Aging Clin Exp Res 2021. doi:10.1007/s40520-020-01678-x. Morris MC, Tangney CC. A potential design flaw of randomized trials of vitamin supplements. JAMA 2011. doi:10.1001/jama.2011.383