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In this detailed nursing lecture, we cover everything you need to know about Sickle Cell Disease (SCD). From the genetic inheritance patterns and pathophysiology to acute management of vaso-occlusive crises and long-term care plans. This video is perfect for nursing students, medical professionals, and anyone looking to understand Sickle Cell Anemia in depth. We also discuss the specific epidemiology of SCD in Kenya and Sub-Saharan Africa, along with the latest treatment advances. Key Topics Covered: Genetics: Autosomal recessive inheritance & HbS mutation. Pathophysiology: Polymerization, sickling, and vaso-occlusion. Clinical Presentation: Dactylitis in infants, acute chest syndrome, and stroke risk. Management: Pain management, hydration, antibiotics, and Hydroxyurea. Rx Timestamps: 00:00 - Introduction & Epidemiology (Global & Kenya) 05:19 - What is Sickle Cell Disease? (Genetics & Inheritance) 15:10 - Pathophysiology: Polymerization & Vaso-occlusion 18:40 - Hemolysis & Jaundice 23:32 - Clinical Features: Infants vs. Adults 28:04 - Management of Pain & Vaso-occlusive Crisis 32:55 - Infection Management & Admission Criteria 42:24 - Complications: Acute Chest Syndrome & Stroke 48:57 - Priapism: Causes & Management 52:16 - Comprehensive Care Plan: Screening, Vaccination & Prophylaxis #SickleCellDisease #NursingEducation #Pathophysiology #ManualOfNursing #MedicalLecture #Hematology #SickleCellAwareness