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5:14 introduction to periodontal or peri-implant infections 22:29 what is the non-surgical CLEAN&SEAL therapy 23:40 what is the cleaning agent Perisolv - sodium hypochlorite gel? 29:11 scientific evidence for Perisolv 32:43 what is the regenerative agent hyaDENT BG - cross-linked hyaluronic acid gel? 38:25 scientific evidence of hyaDENT BG 44:44 scientific and clinical evidence about CLEAN&SEAL 1:00:00 clinical case of periodontitis 1:10:25 Clinical case with peri-implantitis treated single time with CLEAN&SEAL 1:16:00 surgical case of peri-implantitis 1:17:45 conclusion 1:19:05 Q&A Despite thorough hygiene measures, in many cases, infectious diseases like mucositis, shallow peri-implantitis as well as severe periodontitis cannot be successfully controlled non-surgically and require invasive interventions. The CLEAN&SEAL, applied into periodontal pockets, is a non-surgical therapy contributes to shifting or avoiding surgeries in cases of mucositis, shallow peri-implantitis, and severe periodontitis. Prof Anton Friedmann and Dr Thomas Gottwald cover the scientific and clinical data for the new CLEAN&SEAL therapy for periodontal pockets and peri-implant tissues, it is a method based on a two-step approach: 1. Decontaminate the periodontal pocket by means of mechanical instrumentation supported by an amino acid-buffered hypochlorite cleaning gel (PERISOLV). 2. Filling/Sealing the cleaned periodontal/peri-implant pocket with cross-linked hyaluronic acid (xHyA – hyaDENT BG) to protect from reinfection and to accelerate wound and tissue healing. The course covers the challenges to treating severe periodontitis and peri-implantitis, the current treatment options available, the CLEAN&SEAL protocol, and the scientific and clinical data about CLEAN&SEAL (i.e. Perisolv and hyaDENT BG)