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Thursday, April 5, 2012 • 2:15-2:30 PM Authors: Logan Carr*, Joseph Brancheck*, and Dhaval Patel Cutaneous squamous cell carcinoma (SCC) is the second most common type of skin cancer in the United States and accounts for 20 percent of non-melanoma skin cancers; in addition, it is the second most common cancer overall in Caucasians. Due to an aging population and increasing sun exposure, the number of cutaneous carcinomas is increasing and the incidence is estimated to be over three million annually. Unlike the more common basal cell carcinoma, SCCs are more likely to metastasize. This makes a timely diagnosis and treatment even more important because a long delay before surgical removal of SCC is associated with an increased risk of invasive SCC. SCC is already associated with a high cost and morbidity which becomes even higher when the cancer becomes invasive. The patient in this case did not have insurance and, therefore, delayed treatment of his SCC for two years. His treatment at two years required 8 hours of operation time and the expertise of a neurosurgeon, plastic surgeon, and otolaryngologist as well as many days of hospital stay. This case study exemplifies the advantage of primary and secondary prevention as well as the treatment of advanced head and neck SCCs.