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Running out of time? Need to revise medical syllabus quickly for medicine board exams? Do not worry sqadia.com has got you covered. In this pheochromocytoma lecture, we will quickly outline the important points to remember about pheochromocytoma pathology. We also highlight the pheochromocytoma rule of 10 and learn about the clinical features to accurately diagnose a patient, to immediately treat them. ▬ 📌 What is Pheochromocytoma? ▬▬▬▬▬▬▬▬▬▬ Pheochromocytoma (PHEO or PCC) is a malignant tumor of adrenal medulla. These tumors are said to be composed of chromaffin cells or pheochromocytoma cells, which secrete high amounts of catecholamines including epinephrine and norepinephrine. The triggers of pathogenesis of pheochromocytoma includes stress, physical exercise, cheese, and wine. The cause of pheochromocytoma could be idiopathic (unknown cause) or it could either be genetic. ▬ 📌 Rule of 10’s Pheochromocytoma ▬▬▬▬▬▬▬▬▬▬ The etiology can be chalked down to the “rule of ten in Pheochromocytoma” or also called the “10 percent rule”. This is a fun way of dividing up the distribution and pheochromocytoma histopathology, so it becomes easy to recall during your tests. ✨ 10% familial ✨ 10% malignant ✨ 10% bilateral ✨ 10% multiple ✨ 10% extra-adrenal ✨ 10% in children Keep this rule of 10 in mind, when you are observing a pheochromocytoma patient. ▬ 📌 Pheochromocytoma Pathophysiology ▬▬▬▬▬▬▬▬▬▬ Which clinical features to look for in a typical pheochromocytoma patient? Well keep the following sign and symptoms in mind: ✔️ Episodic headache ✔️ Palpitations ✔️ Sweating ✔️ Polydipsia ✔️ Polyuria ✔️ Postural hypotension ▬ 📌 Pheochromocytoma Diagnosis ▬▬▬▬▬▬▬▬▬▬ Some laboratory tests are required to nail down the diagnosis of pheochromocytoma, by measuring catecholamine (metanephrines) products in blood or urine. We have to pair the laboratory tests of pheochromocytoma with some abdominal imaging tests especially CT or MRI of the abdomen, that may help localize the adrenal tumors. ▬ 📌 Pheochromocytoma Treatment ▬▬▬▬▬▬▬▬▬▬ Now the question arises, how to treat a patient with pheochromocytoma? Pheochromocytoma treatment is a tricky topic. But just keep the following points in mind, watch the full video to learn all the details of each. 🔵 Alpha blockers such as phenoxybenzamine are administered 🔵 Beta blockers such as propanolol 🔵 Surgical excision of the adrenal tumor 🔵 Alternative therapies such as metyrosine So, in this pheochromocytoma lecture, we learned all about the pathology and management in just under 5 minutes! As we said earlier, this lecture is perfect to revise for your tests or medicine board exams! ▬ 🎬 5500+ sqadia.com Medical Videos ▬▬▬▬▬▬▬▬▬▬ 👩🏻⚕️ Accessible Medical Student Education 24/7/365 💡 Simplifying Medical Learning 💪 Study Hard, Dream Big, Achieve More