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Clostridioides difficile (also known as Clostridium difficile or C. diff) is an infection caused by a type of bacteria that make substances (toxins) that harm the gut. C. diff most often occurs in people who are on antibiotics or have been taking them recently. It is also common in patients who have been in a hospital or long-term care facility for some time. People ages 65 and older are at increased risk, as well. Learn more at https://gastro.org/practice-guidance/.... This program was supported by an independent educational grant from Ferring Pharmaceuticals, Inc.