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Date: April 10, 2025 Speaker: Raphiel Murden, PhD, Assistant Professor of Emory University Abstract: Cardiovascular (CV) health in the U.S. has improved since the 1950s, but racial and sex-based disparities remain. Non-Hispanic Black women are at a disproportionately high risk for CV disease, with similar CV rates observed between Black men and women—an anomaly among racial groups. Hypertension (i.e., high blood pressure) is a primary risk factor for CV disease, and blood pressure (BP) fluctuates due to psychological, sociological, environmental, behavioral, and circadian influences. Ambulatory blood pressure monitoring (ABPM) is the gold standard for capturing these variations, providing continuous BP measurements over 24 to 48 hours. This presentation examines ABPM data from a cohort of early-middle-aged Black women (30-45 years) to identify BP correlates that may inform targeted interventions to lower CV disease risk in this vulnerable population. Specifically, we will investigate associations between ABPM data and financial security, stress from loved ones, and the impact of obesity on circadian BP rhythms. Additionally, we will explore whether BP changes before and after the COVID-19 pandemic were influenced by positive psychological factors. Understanding these relationships may provide critical insights into reducing hypertension-related CV disparities among Black women, ultimately guiding future research and clinical strategies aimed at improving long-term CV health outcomes in this high-risk group.