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[Acknowledgements] First and foremost, I would like to express my deepest gratitude to my supervisors, Dr. Fabrice BERNARD, Prof. Frédéric GRONDIN and Prof. Siham KAMALI-BERNARD who have guided, motivated and encouraged me to do the right thing even when the road got tough. Especially, thank you so much for providing me such a great opportunity to work with you. Thank for your valuable time on many hours of discussion and meeting. I whole-heartedly appreciate for your great advices and supports toward the success of this PhD study. I am very grateful to Prof. Ali ZAOUI, Prof. Sébastien RÉMOND, Dr. Syed Yasir ALAM, Dr. Tulio Honorio and Dr. Julien Sanahuja for accepting being the reporters and examiners of my dissertation presentations. Thank you for spending your valuable time to read, question and give feedback, which allow me to reflect and foresee my future research. In addition, I would like to show my gratitude again to Dr. Syed Yasir ALAM who gave me not only many great advices and suggestions but also encouragement. You have spent your valuable time to give me an opportunity to explore more on the application of Discrete Element Method via PFC. Next; I would like to thank Dr. Laurent PÉDESSEAU and Dr. Syed Yasir ALAM for being my thesis monitoring committee since the first year of my PhD. Furthermore, I would like to express my appreciation to Dr. Jérôme CLAVERIE for his guidance at the beginning of the journey with Molecular Dynamics simulations via LAMMPS. I also wish to pay my sincere regards to Laboratoire de Génie Civil et Génie Mécanique (LGCGM), Université de Rennes 1, INSA Rennes and Institut de Recherche en Génie Civil et Mécanique (GeM), Nantes Université, École Centrale de Nantes for financial support. Without their support, I would not have an opportunity to work in this project. Moreover, I would like to recognize the invaluable assistance to my colleagues, Jinane Murr and Marinelle EL KHOURY. I also wish to thank all people who I have met during this PhD journey such as Pisey KEO, Piseth HENG, Theany TO, Khundadino LENG, Sokvisal MOM, Yeakleang MUY, Try MENG, Davin SANG, Sounean HENG, Lynita SAROU, Rithymarady HORM, Thaileng OENG, Vanthet OUCH, Vathana PHANG, Bunpo EAR, Pengzhi WANG, Elodie PIOLET, Mickael Le VERN, Siddhartha Harsha OMMI, Julien BOMBERAULT and many others for being around. Thank you for your advice, suggestion, support, motivation and encouragement. Last but not least, I would like to express my special thank toward my beloved parents, Sophat SOU, Bunthoeun SIEK, Narin HOK and Maty SRUN for their encouragement and motivation during my PhD study and their support for my study since I was a child. Without their support, I would not be who I am today. Next, I would like to thank my wonderful wife, Rathanaraingsey HOK who always supports, motivates, encourages and loves who I am. I would like to say that I really love you my sweetheart. I also thank my brothers and sisters, Sophanith HOEUN, Dorasy HOK, Phearom UN and Pongvanthorn NARIN. Lastly, I was not present when you breathed your last since I was here doing my research, my three late grandparents. However, I do possess the most vivid memories a grandchild can conjure. Finally, I would like to mention that it would not be possible to complete my PhD thesis without their tremendous support and encouragement in the past few years. They have always been my inspiration to improve myself and to achieve my dream. Therefore, I dedicate this work to them. Please SUBSCRIBE 🙏 & LIKE 😊 Thank for watching See you