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🔹 Simultaneous Surgery for Colorectal Cancer with Liver Metastases — When “One Stage” is Better In selected cases, both the primary tumor and liver metastases can be removed during the same operation. ✅ Fewer hospitalizations ✅ Faster return to systemic therapy ✅ Oncologic outcomes comparable to a staged approach When this approach is suitable: — Oligometastatic liver disease, resectable with R0 margins — Good response to chemotherapy — No severe comorbidities — Decision confirmed by a multidisciplinary tumor board When it’s better not to combine: — Planned major hepatectomy — High-risk rectal surgery with a significant risk of anastomotic leak ⸻ 🩺 Clinical Case 👨⚕️ Male, 55 years old 📌 Diagnosis: sigmoid colon cancer ycT3N0M1a 💉 Treatment: 8 cycles of FOLFOX + cetuximab 📊 Result: multiple liver lesions — complete radiologic regression, single residual subcapsular lesion in segment S3 📝 Tumor board decision: simultaneous surgery 🔪 Procedure: atypical resection of liver segment S3 + sigmoid colectomy ⏱ Duration: 1 hour 45 minutes 🏥 Discharge: postoperative day 5, no complications 💡 A great example where an excellent chemotherapy response and a small-volume liver resection allowed safe simultaneous surgery, completing the surgical stage of treatment in one go.