Macrolides and ketolides скачать в хорошем качестве

Macrolides and ketolides

Clarithromycin, azithromycin, erythromycin, telithromycin (a ketolide) Macrolides are among the antibiotics used most frequently in the outpatient setting because of their broad coverage of respiratory pathogens. Though their coverage is broad, it is not particularly deep, because there is increasing resistance to these agents (especially in Streptococcus pneumoniae). To combat this resistance, the ketolide derivatives (including telithromycin) have been introduced with better coverage of resistant S. pneumoniae. Unfortunately, telithromycin appears to have a significant risk of hepatotoxicity. Erythromycin is the class first antibiotic, it has adverse effects, drug interactions, and frequent dosing.