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Antigens....

Antigens The terms immunogen and antigen are often used synonymously. However, these terms imply two closely related entities. The first describes a molecule that provokes an immune response(immunogenicity) and hence is called an immunogen. The other describes a molecule which reacts with the antibody produced, or with the activated cellular constituents of cell mediated immunity(antigenicity), and is referred to as an antigen. In contrast to this is the hapten. Haptens are small well defined chemical groups such as dinitrophenol (DNP) which are not immunogenic on their own but will react with preformed antibodies. To make a hapten immunogenic, it must be linked to a carrier molecule which is itself immunogenic. Antigens are recognized not only by antibodies, but also by antigen specific T cell receptors. In contrast to immunoglobulins, which usually recognize intact antigens, T cell surface receptors recognize processed antigens on the surface of antigen presenting cells. www.edufine.net