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Wild crop relatives have been playing enormously important roles both in the depiction of plant genomes and the genetic improvement of their cultivated counterparts. Chili peppers (Capsicum spp.) are high value crops consumed daily by near a quarter of the world’s population. We will present a complete framework of these plants through a journey exploring its diversity, taxonomy, conservation and phylogeny. Capsicum comprises 42 species distributed from southern United States to Brazil, Paraguay and Central Argentina, including 5 domesticated species widely used all over the world. After years of studying this genus and based on extensive examinations of collections and field explorations, we provide a comprehensive analysis of the whole genus diversity and evolution, the key characters for the identification of the species, and their conservation assessments. We also present the most recent hypothesis on its phylogenetic structure. Our work have contributed immensely to resolving several fundamental questions, particularly those related to characterization and circumscription of Capsicum species, phylogenetic relationships, evolution and cytological features. For upcoming seminars: https://physaloidseminars.weebly.com/ Follow the conversation on Twitter: #SolSeminarOnline