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SURGERY OF HIGH GRADE GLIOMAS WITH INTRAOPERATIVE FLUORESCENCE "PHOTODYNAMIC SURGERY" Are they worth the fight? Primary brain tumors constitute 2% of all neoplasms in adults and 20% in children, the subgroup called high-grade glioma corresponds to 51.4%. Photodynamic surgery is currently part of the NCCN National, Comprehensive Cancer Network guidelines. It consists of administering to the patient a photosensitizing substance that is captured by the tumor cells. In this way, by applying a special light during surgery using a neurosurgical microscope, it is possible to identify tumor cells stained in intense red or fuchsia, allowing the neurosurgeon to differentiate healthy structures from those that are not healthy and thus completely remove the tumor. minimizing brain damage. We currently have in Ecuador, the surgical microscope with blue fluorescence and the first portable fluorescence-guided surgery system that offers the neurosurgeon greater freedom of movement and positioning, improving the surgical viewing angle without interrupting tumor removal. The new system combines blue light with emission filter glasses that provide a bright fluorescent display. It has a light transmission of greater than 91%, allowing brighter fluorescence to be viewed in greater detail. The purpose of our treatment is to achieve a more precise surgery through a better visualization of the tissue, which will have an impact on improving the quality of life and increasing disease-free survival "Yes, there is light at the end of the scalpel"