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Monitoring & Follow Up of Patients With CHB

In this educational video, Dr. Kimberly Brown, transplant hepatologist at Henry Ford Hospital, reviews key strategies for monitoring and managing patients with chronic hepatitis B in clinical practice. She outlines the primary goals of treatment—preventing progression to cirrhosis, liver cancer, liver failure, and transplantation while also reducing the risk of viral transmission. The discussion highlights updated AASLD hepatitis B guidance, including how clinicians identify patients who require treatment and how to monitor those considered inactive carriers through regular laboratory testing, HBV DNA monitoring, and fibrosis assessment. Dr. Brown also explains best practices for ongoing follow-up of patients on antiviral therapy, emphasizing viral suppression monitoring, medication adherence, and hepatocellular carcinoma surveillance with ultrasound and alpha-fetoprotein in appropriate patients. Additional topics include counseling patients on transmission prevention, screening and management during pregnancy, and the importance of hepatitis B testing before chemotherapy or immunosuppressive therapy to prevent viral reactivation. This overview provides practical guidance for clinicians and advanced practice providers caring for patients with chronic hepatitis B.