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Quantitative Magnetic Resonance Imaging Conference: Applications in Neurodegeneration (October 26-28th 2022) Multiparametric Mapping - Trainee talk #2 Camille Coustaury - Spinal cord qMRI is sensitive to microstructural changes in patients with Parkinson’s disease Biography: Second year Master's student in engineering at the "Institut Polytechnique de Paris" Abstract: Parkinson Disease (PD) is the most common neurodegenerative movement disorder with a 1% prevalence for the 60+ age groups. The disease is physiologically characterized by the death of dopaminergic neurons causing motor and balance disorders. Quantitative magnetic resonance imaging can be used to search for potential PD biomarkers in the spinal cord. In this study, we acquired T2*-weighted data and computed magnetization transfer ratio (MTR) in 79 patients. Results include regressions of age-corrected metrics on the UPDRS score in several SC regions and suggest that qMRI is sensitive to microstructural changes in patients caused by the disease. You can follow the qMRI Conference on Twitter @qMRI_conference Organizing Committee Dr. Mallar Chakravarty (@mallarchkrvrty1) Dr. Christine Lucas Tardif (@tardiftweets) Dr. Christopher Rowley (@rowleycd) Aurélie Bussy (@AurelieBussy) Olivier Parent (@oparent41)