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Poop. You flush it, and usually that’s the end of the story. But to scientists like Mark Smith, poop is more than just waste – it’s medicine. Join Mark Smith and Jack Gilbert for a Reddit AMA on Tuesday, March 6th! Follow us @TangledBankHHMI for more details. A healthy intestinal tract is teeming with trillions of microbes, which generally keep us infection-free by fending off attacks from bad bacteria that make us sick. But sometimes, bad bacteria like Clostridium difficile can take hold, causing chronic and painful diarrhea, or even death. “C Diff” is normally treated with an intensive course of antibiotics, but this sometimes makes things worse by weakening the gut microbiome and leaving it susceptible to further infection. Mark Smith things he has a solution: poop. He’s treating patients who aren’t helped by the standard antibiotic treatment with new “fecal transplants.” It’s exactly what it sounds like—transplanting stool from healthy donors into sick patients. Doctors have observed remarkable recovery rates with this novel technique… but how does it work? Subscribe for more episodes every Monday! And don't forget to find us on Facebook or Medium for articles and infographics that explore beyond each episode: On Facebook: / hhmisciencemedia On Medium: / hhmi-science