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Abstract: Regulatory activity targeting fluorinated materials has increased globally, which may impact the ability to select and utilize the optimal materials to achieve performance and safety criteria in cable and connectivity designs. Many essential use cases have been identified both for safety and performance across a wide range of applications, such as, clean energy, transportation, aerospace, automation, advanced electronics, oil & gas, defense, security, medical, pharma, and more. There are many questions and misconceptions across these industries, ranging from the chemistries of such materials to the development and deployment of responsible manufacturing technologies. This work provides an overview of the regulatory landscape, examples of fluoropolymer materials of critical essentiality, and a deeper understanding of the sustainability impact of responsible manufacturing investments and analytical expertise needed to move forward. Presenter Bio: Dr. Bianca Hydutsky is the Global Technology Director for the Advanced Performance Materials Division of The Chemours Company, LLC. She received her B.S. in Chemistry from Millersville University and Ph.D. in Chemistry from The Pennsylvania State University.