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Royal inbreeding, especially within the Habsburg dynasty, led to a condition famously known as the "Habsburg jaw" or mandibular prognathism. This was a prominent physical feature where the lower jaw jutted forward noticeably, often causing speech and eating difficulties. The Habsburgs, in an effort to preserve political power and royal bloodlines, frequently married within their own family—sometimes between close relatives like uncles and nieces or cousins. Over generations, this extreme inbreeding increased the chances of recessive genetic traits expressing themselves, including the distinct jawline and other health issues. The most well-known example is King Charles II of Spain, who suffered from severe physical and intellectual disabilities, likely due to generations of genetic isolation. The Habsburg jaw stands as a striking historical example of how inbreeding can amplify hereditary traits and lead to serious health consequences. #genetics #royals #interesting