Hepatocellular Carcinoma | HCC | From CMDT 2025 & Harrison 21st Edition | All you need to know! скачать в хорошем качестве

Hepatocellular Carcinoma | HCC | From CMDT 2025 & Harrison 21st Edition | All you need to know!

Hepatocellular Carcinoma (HCC): Everything You Need to Know! Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, which arises from the parenchymal liver cells, i.e., hepatocytes. It often develops in the context of cirrhosis and chronic liver disease, especially in patients with cirrhosis due to hepatitis B or hepatitis C infection, excessive alcohol use, or nonalcoholic fatty liver disease (NAFLD or NASH). Symptoms and Early Detection: The early stages of HCC may be asymptomatic, but as it progresses, patients may experience symptoms such as jaundice, unintentional weight loss, abdominal pain, and swelling. Regular screening with ultrasound and blood test, i.e., serum alpha-fetoprotein levels (AFP), is recommended for high-risk groups to diagnose the disease early. Risk Factors, Etiology and Prevention: Major risk factors include chronic hepatitis B or C infections, cirrhosis, excessive alcohol use, and metabolic conditions. Vaccination against hepatitis B virus, lifestyle modifications, and prompt treatment of hepatitis B & C can significantly lower the risk of developing HCC and improve the outcome of the patients. Diagnosis and Treatment: Diagnosis typically involves imaging studies (CT scan or MRI scan). Liver biopsy may be needed in some cases. Treatment options depend on the stage of the cancer and include surgical resection of tumor, liver transplantation, local ablation therapies, and systemic therapies like molecular targeted therapies and immunotherapy Prognosis: The prognosis for HCC depends on the stage at diagnosis and liver function. Early detection greatly improves treatment outcomes. Patients should seek support from oncologists, liver disease experts, and patient support groups for supportive care. DISCLAIMER: All the videos and material shared on this channel is designed purely for educational purposes. As everyone's situation can vary, it's recommended to obtain tailored guidance from your treating physician and healthcare professional. Thanks for watching! I hope you find this video useful and helpful. Please like, share, and subscribe to my channel for more useful information. Stay Blessed! All the Best! SBP:    • Spontaneous Bacterial Peritonitis in Liver...   Time Stamps: 00:00 HCC 00:25 Introduction 00:39 Other Uncommon Tumors of Liver & Biliary Tree 01:00 Definition of HCC 01:14 Definition of Cholangiocarcinoma 01:24 Gender in HCC 01:35 Risk Factors & Etiology 02:00 Family History of HCC 02:22 Factors which appear protective in HCC 02:40 Signs & Symptoms 03:14 Physical Findings 03:28 Laboratory Findings 04:31 Diagnostic Investigations 05:16 Harrison Table-1 06:50 Stringent Criteria 07:23 Indications of Liver Biopsy in HCC 07:40 Complications of Liver Biopsy 07:49 Special Stains for Liver Biopsy to diagnose HCC 08:15 Staging System of HCC 08:30 Barcelona Clinic Liver Cancer Staging System 09:06 Treatment 09:21 Parameters for Treatment Strategy 09:35 BCLC Stages for HCC & Therapeutic Strategy 09:43 BCLC Stages 11:08 Harrison Table-2 12:08 Other Staging Systems 12:24 MDT Approach 12:41 Surgical Therapies 13:36 Contraindications & Complications 14:00 Liver Transplant 15:08 Radio-frequency Ablation 16:10 Chemoembolization 17:32 Complications of TACE 17:51 Other treatment options 18:18 Systemic Therapies 19:37 Molecular Targeted Therapies 20:17 Immune Checkpoint Inhibitors 20:38 VEGFR Antibodies 21:09 Modified Response Evaluation Criteria in Solid Tumor 21:49 Screening & Prevention 22:52 Prognosis 23:12 Thank you