HIV Life Cycle, AIDS, and HIV Treatment (HAART) скачать в хорошем качестве

HIV Life Cycle, AIDS, and HIV Treatment (HAART)

How does HIV and AIDS work? The HIV replication process and life cycle can be long and confusing. In this video, HIV, AIDS, and HAART is explained. More specifically, how HIV enters the body, how it infects our cells and how it uses our cells to replicate itself is gone over in a detailed yet digestible way. Gone untreated, HIV causes AIDS by killing off our white blood cells ( specifically our T helper cells). Exactly how this happens is gone over in a fun and educational way. With proper treatment HIV viral loads can go down to undetectable levels. With undetectable levels HIV cannot be spread via unprotected sex. Undetectable = Untransmittable. How HAART drugs bring an HIV viral load down to undetectable levels is gone over in great detail and explains how there is a drug to stop many steps of HIV’s replication process. Timestamps Ways HIV is transmitted 0:00 How HIV enters our body 0:40 What cell's HIV infects 1:40 Size of HIV 2:11 HIV infecting a cell 2:32 HIV replication 4:00 How HIV causes AIDS/ HIV infected T Cell death 8:28 How HIV causes AIDS/ Non HIV infected T Cell death 9:04 AIDS 10:59 HIV vaccines explained 11:40 HAART/ HIV treatments 12:17 Undetectable = Untransmittable 14:44 Why HIV has no cure yet 15:10 Outro 15:46 Sources: Khan academy is the most thorough source, use them for more detailed explanations. I used them as a guide for this video. Here is their HIV playlist link:    • HIV/AIDS   Campbell, E. M., & Hope, T. J. (2015). HIV-1 capsid: the multifaceted key player in HIV-1 infection. Nature reviews. Microbiology, 13(8), 471–483. doi:10.1038/nrmicro3503 Pyroptosis Drives Both CD4 T Cell Death And Chronic Inflammation In HIV-Infected Lymphoid Tissues http://www.croiconference.org/session... Transcription: http://www.microbiologytext.com/5th_e... HIV Size: Compared with overview in: Fisher, Bruce; Harvey, Richard P.; Champe, Pamela C. (2007). Lippincott's Illustrated Reviews: Microbiology. Lippincott's Illustrated Reviews. Hagerstown, MD: Lippincott Williams & Wilkins. p. 3. ISBN 978-0-7817-8215-9. CD4 Count, HIV, and AIDS: Test and Results, What They Mean - WebMD Red blood cell size: Mary Louise Turgeon (2004). Clinical Hematology: Theory and Procedures. Lippincott Williams & Wilkins. p. 100. ISBN 9780781750073. https://en.wikipedia.org/wiki/Red_blo... https://en.wikipedia.org/wiki/White_b... https://en.wikipedia.org/wiki/Dendrit... Next-Generation mRNA Sequencing Reveals Pyroptosis-Induced CD4+ T Cell Death in Early Simian Immunodeficiency Virus-Infected Lymphoid Tissues Wuxun Lu, Andrew J. Demers, Fangrui Ma, Guobin Kang, Zhe Yuan, Yanmin Wan, Yue Li, Jianqing Xu, Mark Lewis, Qingsheng Li Journal of Virology Dec 2015, 90 (2) 1080-1087; DOI: 10.1128/JVI.02297-15 Undetectable = untransmitable: Rodger, Alison J.; Cambiano, Valentina; Bruun, Tina; Vernazza, Pietro; Collins, Simon; van Lunzen, Jan; et al. (2016). "Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy". JAMA. 316 (2): 171–181. doi:10.1001/jama.2016.5148. PMID 27404185. Rodger, A. (for the PARTNER study group) (July 2018). Risk of HIV transmission through condomless sex in MSM couples with suppressive ART: The PARTNER2 Study extended results in gay men. AIDS2018: 22nd International AIDS Conference. Amsterdam, the Netherlands. Retrieved April 2, 2019 Cohen, Myron S.; Chen, Ying Q.; McCauley, Marybeth; Gamble, Theresa; Hosseinipour, Mina C.; Kumarasamy, Nagalingeswaran; et al. (2016). "Antiretroviral Therapy for the Prevention of HIV-1 Transmission". N. Engl. J. Med. 375: 830–839. doi:10.1056/NEJMoa1600693. PMC 5049503. PMID 27424812. Attributions: Caspase 1 image from Lijealso [Public domain] Protein image modified from Emw [CC BY-SA 3.0 (https://creativecommons.org/licenses/...)] Lymph node drawing was modified from https://commons.wikimedia.org/wiki/Fi...