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ARTICLE: https://oncologytube.com/lung-cancer-... In this video, we dive into the latest updates in lung cancer staging and treatment from the AACR 9th Edition, effective as of April 2025. Learn how changes in the TNM system—especially around N2 and M1C classifications—are reshaping patient care, from downstaging Stage 3A to 2B for surgery to upstaging advanced cases. We also explore cutting-edge therapies like immunotherapy, targeted drugs, and antibody-drug conjugates (ADCs), plus their impact on Stages 3 and 4 lung cancer. With 13 FDA approvals in 2024 and more expected in 2025, the future of lung cancer treatment is evolving fast. Check the timestamps below to jump to specific topics! Subscribe for more updates on medical advancements, and let us know your thoughts in the comments! Timestamps 00:00 - Introduction to Staging Changes 00:03:03 - N2 Disease Updates 00:13:03 - Treatment Options 00:23:23 - M1C Metastatic Disease 00:33:16 - Immunotherapy Advances 00:48:26 - Targeted Therapies 01:03:00 - Antibody-Drug Conjugates (ADCs) 01:40:08 - 2024 Recap & 2025 Outlook 02:04:00 - Downstaging Stage 3 03:34:02 - Multidisciplinary Care 04:25:00 - Future of Lung Cancer