KS Insight: Somatosensation: From Detection to Perception (J8) скачать в хорошем качестве

KS Insight: Somatosensation: From Detection to Perception (J8)

About Keystone Symposia Insights Keystone Symposia Insights are panel discussions recorded on digital video that feature Keystone Symposia meeting organizers discussing the state of their respective fields. These thought leaders provide perspectives on current and future trends. The panel is asked to discuss the following topics: What is the state of this field? (What did we learn at the meeting?) Where is the field heading? What are the opportunities and challenges ahead? ___ Somatosensation: From Detection to Perception (J8) Organizer(s) Alexander Chesler, Sarah Ross and Daniel O’Connor February 2—5, 2020 Keystone Resort • Keystone, CO USA Summary of Meeting: This conference focuses on the neural mechanisms that underlie our sense of touch, body position or proprioception, temperature, itch, and pain, collectively called somatosensation. Somatosensation enables us to feel comfort from a gentle caress, enjoy a cool drink of water on a hot day and coordinate physical movement. It helps us to avoid harm by alerting us to potential dangers in the environment. Somatosensory input evokes intense sensations that produce our strongest emotions, like love and pain, and bind experience to memory. Dysfunction in somatosensation results in clinical conditions that causing suffering like chronic itch or pain, and those that impede normal social interaction like attentional impairment, sleep disruption, or despair. The neural circuits and computations that convert somatosensory input into perception are not well known. However, recent advances in molecular genetics, single-cell sequencing, viral tracing, neuroimaging, high-density extracellular recording, and mouse behavioral paradigms are giving rise to breakthroughs in our understanding of the neural basis of somatosensation. This conference will provide a forum for molecular-geneticists, physiologists, behaviorists, and computational scientists using a variety of approaches including in vivo recordings, population imaging, real-time manipulation of neurons in awake, behaving animals, advanced microscopic approaches to understand connectivity, and computational approaches to model somatosensation. Bringing together somatosensation researchers who do not normally have the opportunity to interact will enable new collaborations and idea generation. Our goal is to develop a blueprint for understanding how specific modalities, like touch, temperature, itch and pain, are detected on a molecular level in the skin, transmitted by neurons and experienced as emotion or sensation. We anticipate this meeting will be a landmark event in somatosensory research. ___ Copyright Keystone Symposia, 2020. All rights reserved. About Keystone Symposia: Keystone Symposia is a 501(c)(3) nonprofit organization founded in 1972 that convenes 50-60 open, international scientific research conferences each year across the full range of the life sciences – from cardiovascular disease to immunology to neurobiology. The conferences accelerate life science discovery by bringing together and fostering collaboration among the world’s leading and next generation of research scientists. Visit Keystone Symposia at: https://www.keystonesymposia.org Visit Virtual Keystone Symposia at: https://virtual.keystonesymposia.org/ For more videos:    / keystonesymposia   Follow us on Twitter:   / keystonesymp   Like us on Facebook:   / keystonesymposia   Link to us on LinkedIn:   / keystone-symposia-on-molecular-and-cellula...