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Esophageal cancer is among the 6th to 8th cause of cancer mortality according to the Global Cancer Observatory. The esophagus is a muscular tube that connects the throat to the stomach. Its symptoms cause a significant impact on patients lives and are often: swallow disorder (dysphagia), unintentional weight loss, heartburn and chest pain. The early treatment for esophageal cancer is imperative for a better prognosis and enhances the chance of the patient survivor. Esophagectomy has an important role in the cancer treatment and minimally invasive approach has been achieving an increasingly solid result in recent years. The ISDE (International Society for Diseases of the Esophagus) hosted a virtual tumour board on the multidisciplinary management of esophageal neoplasm that touched on cancer surgery, oncological treatment, management of surgery complications and endoscopic treatment. This recording was part of the Virtual Tumour Board on Esophageal Neoplasm held on March 23, 2021, moderated by Simon Law, University of Hong Kong (Hong Kong) and Richard van Hillegersberg, University Medical Center Utrecht (The Netherlands). Find out more at https://www.isde.net/esophageal-cancer Watch other videos from this virtual tumour board Case 2: Shifting boundaries in T1b esophageal cancer • Shifting boundaries in T1b esophageal canc... Case 3: Oligometastatic disease • Oligometastatic disease: Esophageal Neopla... Case 4: Unresectable Case • Unresectable case: Esophageal Neoplasm Case 4 Check out the Esophageal Cancer playlist • Esophageal Cancer --------------- Simon Law presents the first case in this video of involving post chemoradiation esophageal stenosis. Four cases were presented during this virtual tumour board and panelists were invited to comment on treatment and managements approaches from their respective regions and disciplines. Attendees were invited to submit their perspectives via audience polling and chat directly with panelists during this live presentation. ISDE wishes to recognize and thank the following individuals for their contributions to this virtual tumour board: • Trevor Leong, Radiation Oncologist, Peter MacCallum Cancer Centre (Australia) • Daniela Molena, Surgeon, Memorial Sloan Kettering Cancer Center (USA) • Ken Kato, Medical Oncologist, National Cancer Center Hospital (Japan) • Christiane Bruns, Surgeon, University Hospital Cologne (Germany) • Jacques Bergman, Gastroenterologist (The Netherlands)