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In this episode, Dr. Jennifer Young Pierce talks with Mary Lucy Mattei, a nurse practitioner specializing in gynecologic oncology, all about chemotherapy basics—"Chemo 101." They explain what chemotherapy is, why it's used, and what patients can expect during treatment. Mary Lucy shares practical advice, like bringing snacks, comfortable clothes, and something to do during long treatment days. She covers common side effects, such as fatigue, nausea, constipation, hair loss, and nerve problems, and provides guidance on how to manage them. They discuss the emotional impact of losing hair and explore options such as wigs, scarves, and even eyebrow tattooing. Mary Lucy also talks about ways to prevent and treat neuropathy and stresses the importance of staying hydrated and keeping a normal routine as much as possible. Both encourage patients to ask questions and reach out for support, promising that the care team is there to help every step of the way. The episode aims to remove some of the fear around chemo and help patients and families feel prepared and supported.