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B. Malique Jones, graduate student (Michigan State Univ; Beaumont-Oakland Univ P20 Center) discusses the urothelium drives changes to contractility that mimic neurogenic inflammatory signaling; Ramy Goueli, MD (University of Texas Southwestern) discusses neuromodulation in neurogenic lower urinary tract dysfunction; LaTasha Crawford, VMD, PhD, DACVP (K12 Scholar, UW-Madison KURe Program) discusses what can nerve injury tell us about urologic pain syndromes? Sensory ganglia as a site for somato-visceral crosstalk; and Kimberly Keil Stietz, PhD (UW-Madison U54 O’Brien Center; also Opportunity Pool Awardee, Stanford University U54 O’Brien Center) discusses the role of developmental exposure to environmental neurotoxicant, PCBs, on the lower urinary tract at the 2022 Annual CAIRIBU* Meeting. *Collaborating for the Advancement of Interdisciplinary Research in Benign Urology (CAIRIBU) is an umbrella organization that brings together NIDDK-funded investigators devoted exclusively to investigating benign genitourinary diseases and disorders. A primary objective of CAIRIBU is to encourage interdisciplinary interactions and build effective research collaborations that can tackle the most critical questions related to benign prostatic hyperplasia, urolithiasis, bladder disorders, urinary tract infection, pelvic pain, and genitourinary developmental disorders. Visit the CAIRIBU Community website here: https://cairibu.urology.wisc.edu/.