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Watch the Full Video at https://www.jove.com/v/58210/dynamic-.... Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease - a 2 minute Preview of the Experimental Protocol Emily Becker, Sebastian Schramm, Marie-Theres Binder, Clarissa Allner, Maximilian Wiendl, Clemens Neufert, Imke Atreya, Markus Neurath, Sebastian Zundler University of Erlangen-Nuremberg, Department of Medicine 1; Dynamic adhesion of immune cells to the vessel wall is a prerequisite for gut homing. Here, we present a protocol for a functional in vitro assay for the impact analysis of anti-integrin antibodies, chemokines or other factors on the dynamic cell adhesion of human cells using addressin-coated capillaries. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments