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The real disruption in orthopedics isn’t a robot, implant, or incision. It’s a new way of thinking about recovery. At AHF 2025, Dr. Andrew Wickline shared how he re-engineered his entire care pathway to achieve 95% opioid-free recovery after hip and knee replacement, through swelling control, inflammation management, and patient education. This talk challenges surgeons to look beyond the hour in the OR, and take ownership of the 90 days that define true success. Key Insights: The link between swelling, inflammation, and opioid dependence Protocols for TXA, cryotherapy, and compression that reduce pain naturally Why education is the most powerful technology in recovery How to optimize before, during, and after surgery for better outcomes A personal call to confront opioid overuse in orthopedics “Swelling is the enemy hiding in plain sight.” Dr. Andrew Wickline explains how controlling it changes everything — pain, recovery, and the need for opioids. Chapters / Timestamps: 00:00 Introduction – Looking beyond the OR 01:09 Why swelling matters 03:37 How swelling drives pain and opioid use 05:54 Education as the real game-changer 07:28 Cold compression, TXA, and step control 09:23 Extended TXA and outcomes 10:40 Amino acids, lymphatic stimulation, and recovery 12:49 The path to 95% opioid-free surgery 13:51 A call to surgeons: recovery is our next frontier