DevoWorm (2025, #17): Connectomic Models and the Phase Transitions of Cellular Evolution скачать в хорошем качестве

DevoWorm (2025, #17): Connectomic Models and the Phase Transitions of Cellular Evolution

Attendees: Morgan Hough, Soham Shaw, Susan Crawford-Young, Hussain Ather, Lalith Bharadwaj, Jesse Parent, and Bradly Alicea Discussing advances in connectomics (2.0) and the role of simulating connectomes for understanding the brain. New developments in Drosophila connectomes. Reductionism and "cells for x" versus emergent behaviors. Systems-level networks vs. subnetworks. All-to-all connectivity vs. sparse connectivity in nervous systems, how structure provides function. Parallels between mechanical and neural (communicative) connectivity. Updates on the group's medical physics and imaging project. The role of gene regulation in the eukaryotic evolutionary transition: more complex proteins enable a more rapid and efficient exploration of protein space. References: Dattaro (2025). Connectomics 2.0: Simulating the brain. The Transmitter, May 2. https://www.thetransmitter.org/connec... Muro et.al (2025). The emergence of eukaryotes as an evolutionary algorithmic phase transition. PNAS, 122(13), e2422968122.