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Hofmann rearrangment Reaction

In this video, I demonstrate the Hofmann Rearrangement, an important organic chemistry reaction where a primary amide is converted into a primary amine with one fewer carbon atom. The reaction typically uses bromine (Br₂) and a strong base such as sodium hydroxide (NaOH) to transform the amide into an amine through an isocyanate intermediate. 🔬 What you will learn in this video: • What the Hofmann Rearrangement reaction is • Reagents and reaction conditions • Step-by-step reaction mechanism • Formation of the isocyanate intermediate • Why the product has one carbon less than the starting amide • Applications in organic synthesis This reaction is very useful in amine synthesis and is commonly taught in advanced organic chemistry courses. #OrganicChemistry #HofmannRearrangement #NamedReactions #ChemistryLab #ReactionMechanism