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Tubular Adenoma - Adenomatous Polyp

Both tubular adenomas and adenomatous polyps are types of colorectal polyps that have the potential to develop into colorectal cancer. Their histopathological features share similarities, but there can be slight differences in appearance. Tubular adenoma: Histologically, tubular adenomas are characterized by well-defined tubular structures lined by dysplastic glandular epithelium. The glands are elongated and closely packed, with cells showing varying degrees of dysplasia. The nuclei might be enlarged, hyperchromatic (darkly stained), and there might be increased mitotic activity. Dysplastic changes can range from mild to severe. Adenomatous polyp: The term "adenomatous polyp" is often used to describe a variety of polyps with glandular tissue growth that can potentially progress to cancer. They can include tubular, villous, or tubulovillous adenomas. The distinction lies in the structure of the glands and the level of dysplasia. Tubular adenomas consist mainly of tubular glands, while villous adenomas have finger-like projections called villi. Tubulovillous adenomas have a combination of both tubular and villous features. In both cases, careful examination of the tissue is necessary to assess the degree of dysplasia and any potential signs of malignancy. Regular screenings and polyp removal are recommended to prevent the development of colorectal cancer.