Our DNA changes as we get older?! DNA Cytosine methylation with aging. скачать в хорошем качестве

Our DNA changes as we get older?! DNA Cytosine methylation with aging.

DNA encodes all the information needed to construct and program our cells and bodies, consisting of long chains four letters, or bases, A, G, C and T. To help control our gene expression, the DNA can be chemically modified. One such modification is on the C letter, cytosine, and is called methylation. While normally this is a natural and reversible process, it has been found that as we age this modification accumulates in specific regions of our DNA. Indeed, by comparing DNA from over 100 mammalian species and across many types of tissues, it has been shown that the amount of methylation can be used to accurately estimate that age of a given sample. Further work has shown that the rates of methylation generally correspond to the maximum expected lifespan of a mammal, so that the short-lived mouse accumulates the modification far more rapidly than humans do. Together this suggests a unified picture of biological aging across mammalian species. Research from: https://www.nature.com/articles/s4358... https://www.nature.com/articles/s4358... #sciece #blender #biology #dna #aging