Urothelial Carcinoma and Colorectal Cancer Tumor Growth and Metastasis | Protocol Preview скачать в хорошем качестве

Urothelial Carcinoma and Colorectal Cancer Tumor Growth and Metastasis | Protocol Preview

Watch the Full Video at https://www.jove.com/v/59223/patient-.... Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis - a 2 minute Preview of the Experimental Protocol Ravan Moret, Linh Hellmers, Xin Zhang, Jessie Gills, Nathan Hite, Aaron Klinger, Grace A. Maresh, Daniel Canter, Stephen Bardot, David A Margolin, Li Li Ochsner Clinic Foundation, Laboratory of Translational Cancer Research, Institute for Translational Research; Ochsner Clinic Foundation, Department of Urology; Ochsner Clinic Foundation, Department of Colon and Rectal Surgery; University of Queensland, School of Medicine, Ochsner Clinical School; This protocol describes the generation of patient-derived orthotopic xenograft models by intra-vesically instilling high-grade urothelial cell carcinoma cells or intra-rectally injecting colorectal cancer cells into non-obese diabetic/severe combined immunodeficiency (NOD/SCID) mice for primary tumor growth and spontaneous metastases under the influence of lymph node stromal cells, which mimics the progression of human metastatic diseases. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments