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During the 69th session of the Global NMR Discussion Meetings held on June 13th, 2023 via Zoom, Prof. Dominik Bucher gave a talk on the topic "Nano- and Microscale Magnetic Resonance Spectroscopy Using Spin Defects in Diamond". The recording serves as a tutorial. Prof. Dominik Bucher is a Rudolf-Mößbauer Professor at the Technical University of Munich (TUM), Germany. Website: https://www.ch.nat.tum.de/en/qsens/home/ Google scholar: https://scholar.google.de/citations?u... Twitter: / bucherlab Abstract: Nuclear magnetic resonance (NMR), one of the most powerful analytical techniques in chemistry and life sciences, is typically limited to macroscopic volumes due to its inherent low sensitivity. This excludes NMR spectroscopy from the analysis of microscopic sample sizes, such as in single-cell biology or microfluidic applications. In recent years, it has been shown that NMR signals from nano- to microscale volumes can be detected by a new class of sensors - quantum sensors based on defects in the diamond lattice - the nitrogen vacancy (NV) centre. In this talk, I will first introduce NV centres and explain how these atom-sized sensors can be used to detect NMR signals. In the second part, I will provide an overview of this rapidly developing technology and discuss potential applications ranging from surface and materials science to lab-on-a-chip applications. Current organizers: Adrian Draney (Creighton Uni., Chemistry) Amrit Venkatesh (Lyndon Emsley Lab, EPFL) Asif Equbal (New York Uni., Abu Dhabi) Blake Wilson (Robert Tycko Lab, NIH) Michael Hope (Lyndon Emsley Lab, EPFL) Mouzhe Xie (Maurer Lab, Uni. Chicago) Nino Wili (Niels Chr Nielsen Lab, Aarhus Uni.) Tamar Wolf (Lucio Frydman Lab, Weizmann Institute of Science)