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Hormone Replacement Therapy or Women

Hormone replacement therapy reduces age related bone loss; reduces mortality from osteoporosis; reduces age related muscle loss; increases muscle strength; reduces hair loss; maintains dermal thickness; improves elasticity of skin; reduces facial wrinkling; and improves cosmetic appearance. However not all women are good candidates for hormone replacement therapy, especially women with a history of breast cancer, uterine cancer or unexplained uterine bleeding, history of deep venous thrombosis or history of cardiovascular disease or stroke. Not all forms of estrogen replacement therapy are the same. The transdermal estrogen preparations have fewer side effects than estrogen given orally. Hormone replacement therapy with estrogen increases the risk of death from breast cancer by about 2 breast cancer deaths were 10,000 women. However the overall mortality of osteoporotic fractures is 24% after 1 year and 62% after 5 years and hormone replacement therapy reduces osteoporosis by 30-50 % in postmenopausal women.