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Rh incompatibility in pregnancy nursing NCLEX maternity review: management, pathophysiology, Rhogam shot, and hemolytic disease of the newborn. What is Rh incompatibility? It occurs when a father who is Rh-positive and a mother who is Rh-negative have a baby that is Rh-positive. The baby's Rh-positive blood will leak into mom’s circulation (most likely during delivery), and this will cause the mother's to build antibodies. The baby of the first pregnancy is not typically harmed. However, the baby during the second pregnancy, who is Rh-positive, will be affected because those antibodies created during the first pregnancy are in mom's circulation. These antibodies will attack the baby's red blood cells. This will lead to hemolytic disease of the newborn and cause: anemia, jaundice, heart failure, swelling/edema, splenomegaly along with hepatomegaly. The key is to keep mom from being sensitized, which is done through giving her a medication called Rhogam. This medication is given at 28 weeks and again at 72 hours after delivery if the baby is Rh-positive. More Maternity Lectures: • Maternity Nursing Lectures Notes: http://www.registerednursern.com/rh-i... Instagram: / registerednursern_com Facebook: / registerednurserns Subscribe: http://www.youtube.com/subscription_c... Nursing School Supplies: http://www.registerednursern.com/the-... Check out other Videos: / registerednursern All of our videos in a playlist: • Insulin Onset Peak Duration Mnemonic Nursi... Popular Playlists: NCLEX Reviews: • NCLEX Study Strategies Fluid & Electrolytes: • Fluid and Electrolytes Nursing Nursing Skills: • Nursing Skills Videos Nursing School Study Tips: • Nursing School Study Tips Nursing School Tips & Questions" • Nursing School Tips & Questions Teaching Tutorials: • Teaching Tutorials Types of Nursing Specialties: • Types of Nursing Specialties Healthcare Salary Information: • Healthcare Salary Information New Nurse Tips: • New Nurse Tips Nursing Career Help: • Nursing Career Help EKG Teaching Tutorials: • EKG/ECG Interpretation Dosage & Calculations for Nurses: • Dosage Calculations Nursing Diabetes Health Managment: • Diabetes Health Managment