Short and Long Read Sequencing for AAV Characterization: BIO-ASGCT CGT Science Series скачать в хорошем качестве

Short and Long Read Sequencing for AAV Characterization: BIO-ASGCT CGT Science Series

The BIO-ASGCT Cell and Gene Therapy (CGT) Science Series is a quarterly seminar series focused on scientific topics related to cell and gene therapy products. The CGT Science Series is intended to foster scientific exchange between BIO, ASGCT, and CBER review staff on a variety of topics that span the CGT product lifecycle. The inaugural seminar focuses on NGS characterization of AAV and was presented by Dr. Lauriel Earley. Dr. Lauriel Earley is a Senior Scientist with Shape Therapeutics who has been studying the basic biology of adeno-associated virus for over decade. During her graduate studies at Oregon Health & Science University, she examined the role of assembly-activating protein under the mentorship of Dr. Hiroyuki Nakai. After receiving her PhD, she joined Dr. Jude Samulski's laboratory at the University of North Carolina, Chapel Hill and took on a project to characterize the intrinsic promoter ability of the inverted terminal repeat sequences from various AAV serotypes. Dr. Earley joined Shape Therapeutics in 2019 and is currently leading their vector platform development team. In addition, Dr. Earley has been an active member of ASGCT since 2012 and is currently serving on the Patient Outreach Committee.