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How do you turn a bold idea into a national institution that changes lives? In this episode of All About Business, James speaks with Jenifer Rosenberg OBE, entrepreneur in fashion and social impact leader, about building purpose-driven organisations that create lasting change. Jenifer shares her journey from spotting a gap in support for families facing serious illness, to co-founding Heart Cells Foundation and growing it from a kitchen-table startup into a nationally recognised charity. She reflects on navigating funding challenges, building credibility with clinicians and policymakers, and leading through the emotional realities of mission-led work. The conversation explores scaling a purpose-driven organisation sustainably, balancing commercial discipline with social impact, and the importance of governance, partnerships, and long-term strategy. Jenifer also shares lessons from stepping back from founder leadership, earning an OBE, and staying resilient while driving systemic change. A thoughtful conversation about entrepreneurship with purpose, leading with conviction, and building something that truly lasts. Timestamps 02:18 From post room to senior role 08:07 Quality and innovation with Marks & Spencer 16:28 Branching out into fashion 26:40 The power of innovation 30:23 A personal journey with heart failure 35:24 Founding the Heart Cells Foundation 48:37 Maintaining energy and health Follow James Reed on LinkedIn: / chairmanjames Follow Jenifer Rosenberg OBE on LinkedIn: / jenifer-rosenberg-aa961a156 Find out more the Heart Cells Foundation here: https://www.heartcellsfoundation.com/ Be part of the million job giveaway: https://reed.co.uk/millionjobgiveaway All About Business is brought to you by Reed Global. Learn more here: https://www.reed.com/?utm_medium=AABs... This podcast was co-produced by Reed Global and Flamingo Media. If you’d like to create a chart-topping podcast to elevate your brand, visit: http://flamingo-media.co.uk/