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2.5 million Americans. $51 billion annual cost. Decades of medical dismissal. ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) isn't "just being tired." It's a profound multi-systemic biological disorder that ruins lives—and the medical system has failed patients for 40 years. This clip reveals the true scale of ME/CFS, why it's been so neglected, and what makes it fundamentally different from normal fatigue. 🔬 KEY POINTS: 2.5 million US patients (conservative estimate, likely higher) $51 billion annual economic burden in US alone Multi-systemic disease affecting: energy, cognition, immunity, autonomic function Post-exertional malaise (PEM): hallmark symptom that defines ME/CFS Viral/bacterial triggers common (EBV, flu, COVID-19) Host's dysregulated response (not the pathogen itself) Medical gaslighting history ("it's psychological") Research underfunding compared to disease burden 🔑 KEY INSIGHT: "This is a profound, multi-systemic biological disorder. The real culprit appears not to be the initial bug itself, but the host's long-term dysregulated response to it." 💡 TIMESTAMPS: 0:00 - The hidden health crisis 0:45 - Scale: 2.5 million patients, $51 billion burden 1:30 - Why "chronic fatigue" is a terrible name 2:15 - Multi-systemic dysfunction explained 3:00 - Post-exertional malaise (PEM) defined 3:45 - Viral triggers: EBV, flu, now COVID 4:30 - Host response vs pathogen distinction 5:15 - Medical dismissal and gaslighting history 6:00 - Research funding gap 📊 THE NUMBERS: 2.5 million US patients (est. 17-24 million globally) $51 billion annual US economic burden 75% unable to work full-time 25% housebound or bedbound Research funding: ~$15 million/year (compare to MS: $100+ million) 🎓 PERFECT FOR: ME/CFS patients seeking validation Long COVID patients with PEM symptoms Caregivers trying to understand the condition Medical professionals learning about ME/CFS Advocates fighting for research funding This is a clip from Long COVID 101 – Episode 5: "ME/CFS Multi-Omics: The Exercise That Breaks You" 📺 WATCH FULL EPISODE (39 min): • Видео PISODE_ID Complete episode includes: ✅ Multi-omics research methodology explained ✅ Metabolic, proteomic, immune findings ✅ Exercise challenge study results ✅ Mitochondrial dysfunction evidence ✅ Treatment implications ✅ Future research directions 🔗 RESOURCES: ME Action: meaction.net Open Medicine Foundation: omf.ngo Solve M.E./CFS Initiative: solvecfs.org ⚠️ DISCLAIMER: Educational purposes only. Not medical advice. Consult qualified healthcare professionals for diagnosis/treatment. 🎙️ Produced by: Long COVID 101 #MECFS #ChronicFatigueSyndrome #MyalgicEncephalomyelitis #PostExertionalMalaise #LongCOVID #ChronicIllness #InvisibleIllness #MedicalNeglect 🔔 Full Episode 5: • Heightened Immunity Triggers Chronic Fatig... Subscribe for weekly Long COVID and ME/CFS research breakthroughs!