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Find your hyper-personalized thinking partner here: https://heyclarity.me/ Level Up Your LLM Application with an Audit here: https://tinyurl.com/EvalAudit What if aging isn't just biological decay but a loss of purpose? In this conversation with my co-founder Jonathan (CTO of Epistemic Me), we dive deep into Michael Levin's groundbreaking research on aging, goal-directedness, and what it means for how we're building truly personalized AI systems. Jonathan walks me through how cells function as perception-action agents, why morphological goals matter beyond embryonic development, and how this biological framework directly informs how we're building Clarity—an AI thinking partner that understands your belief systems at the deepest level. This isn't surface-level AI talk. We're connecting cutting-edge biology with the future of human-centered AI, personal growth, and what it means to align your being with becoming your best self. Timestamps: 00:00 Introduction: Welcome to the Self-Aligned Podcast 00:06 Today's Topic: Becoming Human, Goals, Information & The Superorganism 01:12 Michael Levin's Paper: Aging as Lost Goal-Directedness 03:24 What is Morphology? Understanding Cellular Communication 05:37 Morphological Set Points & How Cells Know What to Become 06:24 Bioelectric Fields: How Signals Tell Cells Where to Grow 08:39 From Cell-Level to Human-Level: Why Does Retirement Lead to Cognitive Decline? 10:15 Why Human Development Takes 27 Years: The Role of Cultural Information 16:15 Emotional Expression & The Social Self 21:30 Cells as Information Processors: How Cells Make Decisions 29:32 The Superorganism: Why We Need Information Beyond Ourselves 35:45 Representation Systems: From Cells to Democracy 43:25 The Nine Pillars of Health & Self 50:30 Evidencing Belief Systems: How Clarity Helps You Align 58:15 Self-Acceptance vs. The Desire to Improve: Can They Coexist? 01:03:02 Building Clarity: Quantifying Subjectivity in Belief Systems 01:08:30 The Sisyphus Principle: Finding Meaning in Effort, Not Achievement 01:19:25 Looking Into the Abyss: Decision-Making Under Uncertainty 01:20:35 AI as Extension of Information Environment: Writing to Printing to Internet to AI 01:21:22 The AI Alignment Question: What If We Had Perfect Information? 01:28:45 Literacy, Brain Structure & How AI Changes Our Cognition 01:35:20 System Interpretability: Why AI Needs to Understand Human Context 01:40:15 The AI Health Coach Example: Why Personalization Without Context Fails 01:43:05 How We Deal with Depression: Metabolic Health & Self-Acceptance 01:50:30 Mental Health Signals: Recognizing the Invisible Weight of Depression 01:56:00 Closing Thoughts & What's Next for Epistemic Me Follow me on social media: Instagram ► / therobertta TikTok ► / therobertta_ LinkedIn ► / therobertta X ► / therobertta_ Substack ► https://robertta.substack.com/