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SPI webinar

Organised by Alex Williams and Christopher West, International Collaboration On Repair Discoveries, University of British Columbia, Canada Traumatic spinal cord injury (SCI) is a devastating condition that not only impacts motor function, but can additionally impair the sympathetic regulation of the heart and vasculature. While the impact of SCI on blood pressure regulation has received ample attention, the cardiac consequences of SCI are not well-characterized, and have been given little consideration in the clinical management of SCI. In the acute setting, vasopressor-based hemodynamic management is one of the only neuroprotective strategies presently available to clinicians; however, evidence has emerged that this approach may exacerbate spinal cord hemorrhage. Clinical guidelines have yet to consider that acute cardiac dysfunction may contribute to reduced spinal cord perfusion and oxygenation, and as such could represent a favourable target for hemodynamic management. For individuals living chronically with SCI, several interventions have begun to show promise in augmenting the capacity of the heart, including anti-G suits, abdominal binders, respiratory muscle training, neuromodulation, and exercise training. However, the longitudinal changes to the heart following these interventions have not been well studied. In this webinar, Alex Williams and Christopher West outlined the current state-of-knowledge regarding the acute and chronic cardiac consequences of traumatic SCI. They also discussed the potential application of acute and long-term strategies that may optimise cardiovascular outcomes in individuals with SCI.