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✨ Free Guidance For All Nursing Exams: https://docs.google.com/forms/d/e/1FA... AIIMS NORCET 11 | Pharmacology | Nightingale Batch | Demo Class 6 Welcome to Demo Class 6 of the Nightingale Batch for AIIMS NORCET 11! 🏥✨ In this session, we are mastering Pharmacology, one of the most high-yield and crucial subjects for nursing competitive exams. This class is specifically structured to help you simplify complex drug classifications, remember mechanisms of action, and tackle tricky clinical questions for the upcoming NORCET 11 exam. 📝 Class Highlights: Topic: Pharmacology Basics & High-Yield Drugs Subject: Pharmacology Batch: Nightingale Batch (Targeting NORCET 11) Focus: Essential drug classifications, emergency drugs, antidotes, and practical clinical applications for AIIMS. Timestamps- 0:00 Introduction to Pharmacology Demo Class 6 (Nightingale Batch) 1:25 Recap: Pharmacokinetics and Drug Absorption basics 2:25 Defining Bioavailability: The "Liver Toll" Analogy 6:25 Concept Breakdown: Fraction of Dose reaching Systemic Circulation in Unchanged form 8:16 Determining Dosage: Why Bioavailability informs Dose and not Frequency 10:40 Inverse Relationship: High Bioavailability vs. Low Dosage requirements 12:30 Factors Affecting Absorption: Absorption rates and Bioavailability 16:06 Impact of Administration Routes: Oral vs. IM vs. Subcutaneous 18:14 Why IV Route has 100% Bioavailability and bypasses Biological Membranes 20:17 Understanding First-Pass Metabolism (The Liver Toll) 21:36 First-Pass Metabolism vs. Bioavailability: Higher the Toll, Lower the reach 23:17 Case Study: Nitroglycerin (NTG) and its high First-Pass Metabolism 24:55 Sublingual Route Advantages: Speed, Emergency use, and bypassing the Liver 28:10 Pro-Tip: Spitting the extra dose after desirable effect (Sublingual unique feature) 29:22 How to Calculate Bioavailability: Plasma Concentration vs. Time Graph 33:39 Understanding Area Under the Curve (AUC) 36:26 Reference Standards: Why the IV Route is the base for all comparisons 40:36 The Formula: Calculating Oral Bioavailability using AUC (Oral/IV ratio) 44:55 Defining Bioequivalence: Comparing two brands of the same drug 48:31 Exception to Bioequivalence: Why you must never change brands for Phenytoin 51:26 Analyzing the Plasma Concentration Graph: C-Max and T-Max 53:25 Critical Thresholds: Minimum Effective Concentration (MEC) vs. Maximum Tolerable Concentration (MTC) 56:45 Managing C-Max: Keeping drug levels in the Safe Therapeutic Window 58:30 Understanding T-Max (Rate of Absorption) and AUC (Extent of Absorption) 1:02:00 Homework and Summary: Preview of next topic (Drug Distribution) ----------------------------------------------------------- 📢 PDF Notes Available! 📄 Access on PW App under Aarogyam Reloaded (Free Batch) ✨ Get expert guidance for all Nursing Exams - https://shorturl.at/HbvgR ------------------------------------------------------ ✨Nursing Pro 1.0 (2026) for All Nursing Exams: https://physicswallah.onelink.me/ZAZB... ✨Nightingale Regular for AIIMS NORCET 11: https://physicswallah.onelink.me/ZAZB... ✨Nightingale Fastrack for AIIMS NORCET 10: https://physicswallah.onelink.me/ZAZB... ✨Nightingale Regular for AIIMS NORCET 10: https://physicswallah.onelink.me/ZAZB... ✨Nightingale Regular 2.0 for AIIMS NORCET 10: https://physicswallah.onelink.me/ZAZB... ✨Nursing Junction for RRB Staff Nurse : https://physicswallah.onelink.me/ZAZB... ------------------------------------------------------- 📌 PHYSICS WALLAH SOCIAL MEDIA - 🌐 Nursing Wallah Telegram Channel: https://t.me/pwnursing ------------------------------------------------------- 📌 For any Queries or Complaints visit: https://www.facebook.com/nursingwalla... OR give a Missed Call on 07019-243-492 #AIIMSNORCET11 #NORCET2026 #Pharmacology #NursingPharmacology #NightingaleBatch #NursingOfficer #AIIMS #NursingStudent #PharmacologyLectures #NursingExamPrep #FutureNurses