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Assessing and Managing Bleeding Risk in VTE Patients The source provides an in-depth review on how to assess and manage the risk of bleeding in patients being treated for venous thromboembolism (VTE). Authors Frederikus A. Klok and Menno V. Huisman explain that bleeding prediction is crucial throughout the entire course of treatment, from initiation to long-term follow-up, though the specific focus changes at each stage. The article stresses the importance of identifying and targeting modifiable risk factors for major bleeding, such as uncontrolled hypertension or the use of antiplatelet therapy. While acknowledging that widely validated, simple prediction tools are currently lacking, the discussion highlights several established risk stratification schemes, including VTE-BLEED and the ACCP risk table, as practical tools, particularly for determining the safety of extended anticoagulation. Finally, the text offers a practical, phased approach for daily clinical practice, illustrated by two detailed case scenarios.