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The cannabis plant has been used for millennia as a mind altering drug and medicine for many ailments. Prohibition in the United States forced it underground but never prevented its cultivation or hybridization. At San Diego’s Salk Institute, Professor Todd Michael and his research team genetically sequenced 193 strains of cannabis to try to understand just what it’s capable of. “We have this very important crop that people have been using for thousands of years and people know very little about it,” Michael said. “Turns out what we discovered is the plant has a massive amount of potential that we have really just started to understand and really build the tools to try to tap into.” The best known cannabinoid is tetrahydrocannabinol (THC), the one which makes you high. But there are many more, created by a common molecular pathway. Those cannabinoids that result require a lot of abbreviations to describe. Some minor cannabinoids have proven to be pretty powerful. Cannabidiol (CBD) can control epileptic seizures. Anecdotal evidence shows it helps treat anxiety and chronic pain. One cannabinoid with a pretty good story is THC-V. That’s the psychoactive THC minus a couple of carbon atoms. It’s been called "diet weed" because it gives you kind of the opposite of the munchies. A clinical trial showed THC-V was energizing and reduced the appetite. Read the rest of the story at kpbs.org 📝 Thomas Fudge