Vitamin D and Colorectal Cancer скачать в хорошем качестве

Vitamin D and Colorectal Cancer

💊 Vitamin D and Colorectal Cancer — What Does the Science Say? Vitamin D isn’t just about bone health. More and more research shows it plays a role in preventing colorectal cancer (CRC). 🔬 How does it work? • Regulates cell growth and differentiation. • Suppresses chronic inflammation in the intestinal lining. • Its active form (calcitriol) promotes cancer cell apoptosis and inhibits angiogenesis. 📊 What do studies show? • Meta-analyses: higher vitamin D levels are linked to a 20–39% lower risk of CRC. • In the Nurses’ Health Study, women with the highest vitamin D intake had a 58% lower incidence of CRC. • In patients already diagnosed with CRC, vitamin D supplementation was associated with a ~35% reduction in disease progression and mortality (Nature, 2020). ☀️ Sources of vitamin D: • Sunlight — 10–30 minutes per day (in warm seasons). • Diet — fatty fish, eggs, fortified dairy products. • Supplements — only under medical supervision and with lab monitoring. ⚠️ Important: Excess vitamin D can be harmful (hypercalcemia, kidney damage). Optimal 25(OH)D level for prevention: 30–40 ng/mL. ✅ Takeaway: Maintaining adequate vitamin D levels is not a magic cure, but it’s an important part of comprehensive CRC prevention — especially for high-risk groups and people living in areas with limited sunlight. ⸻ 📚 References: 1. Ma Y. et al., Nutrients, 2025 — doi.org/10.3390/nu17081351 2. Ng K. et al., Nature, 2020 — doi.org/10.1038/s41416-020-01060-8