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This review article, titled "Ethical Issues in Clinical Research and Publication," was published in Kosin Medical Journal (Volume 37, Issue 4, 2022, pp. 278-282). The article was authored by Hyoung Shin Lee from the Department of Otolaryngology-Head and Neck Surgery at Kosin University College of Medicine in Busan, South Korea. It aims to review and summarize the fundamental ethical issues in clinical research and its publication process. This review article examines the essential ethical principles that govern clinical research and the subsequent publication of findings. It traces the historical development of these standards, highlighting the Nuremberg Code and the Declaration of Helsinki as foundational frameworks for protecting human participants. The author emphasizes that researchers must prioritize the safety and dignity of individuals through rigorous informed consent processes and oversight from institutional review boards. Furthermore, the text addresses the integrity of the scientific record by defining misconduct, such as data fabrication and plagiarism, while establishing clear criteria for authorship and transparency. Ultimately, the source serves as a guide for maintaining scientific honesty and ensuring that medical advancements do not come at the expense of human rights.