Helicobacter pylori eradication therapy to prevent gastric cancer скачать в хорошем качестве

Helicobacter pylori eradication therapy to prevent gastric cancer

To cite: Ford AC, Yuan Y, Moayyedi P. Gut Published Online First: 23 March 2020. doi: 10.1136/gutjnl-2020-320839. Read the full article here: http://dx.doi.org/10.1136/gutjnl-2020... Objective: Gastric cancer is strongly associated with Helicobacter pylori (H. pylori). We conducted a previous systematic review and meta-analysis that suggested eradication therapy reduced future incidence of gastric cancer, but effect size was uncertain, and there was no reduction in gastric cancer-related mortality. We updated this meta-analysis, as more data has accumulated. We also evaluated impact of eradication therapy on future risk of gastric cancer in patients having endoscopic mucosal resection for gastric neoplasia. Conclusions: There is moderate evidence to suggest that H. pylori eradication therapy reduces the incidence of gastric cancer in healthy individuals and patients with gastric neoplasia in East Asian countries. There also appears to be a reduction in gastric cancer-related mortality.