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Biomarkers of Inflammation Dipnarine Maharaj, MB.ChB, M.D., FRCP (Edin.), FRCP (Glas.), FRCPath, FACP presents at the 17th Clinical Applications for Age Management Medicine Confernce. Inflammaging is an umbrella term covering a multitude of phenomena which involve aberrant glycosylation as well as tissue damage. This damage is reflected in increasing amounts of mitochondrial DNA in the periphery which correlate with levels of inflammatory biomarkers. The characteristics of inflammaging and its contribution to the development of age-associated chronic diseases in humans will be discussed in this presentation. In addition, immune senescence as it relates to aging and inflammation will be presented. Stem cell aging contributes to immune dysfunction. An individual’s own stem cells can be safely transplanted without being rejected by the body’s immune system to treat immune dysfunction. Autologous stem cell therapy is an established treatment for immune dysfunction of blood cancers. In the future it is believed that the need for autologous stem cell therapy will increase as it may offer remedies for strokes and neurodegenerative conditions such as Parkinson’s and Alzheimer’s diseases and chronic diseases such as heart disease as well as diabetes. This presentation focused on clinical aspects of the use of autologous stem cells for regenerative medicine with emphasis on strategies for optimizing their function by reducing inflammation and improvement of immune dysfunction. What is Age Management Medicine? Age Management Medicine is a proactive, preventive approach focused on preservation of optimum human function and quality of life, making every effort to modulate the process of aging prior to the onset of degenerative aging. The basic tenets of Age Management Medicine are patient evaluation through extensive medical history, lifestyle assessment, physical examination and laboratory evaluation to establish personalized proactive treatment plans consisting of proper diet, exercise, stress management and appropriate medical interventions. About AMMG It is the goal of the Age Management Medicine Group (AMMG) to provide education and information on the specialty of Age Management Medicine to physicians and healthcare professionals through evidence-based, continuing medical education conferences, workshops, seminars, publications and Web media. The Group consists of leading industry healthcare professionals, physicians, practitioners, researchers, medical associations and providers of products and services.