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This talk was given at a local TEDx event, produced independently of the TED Conferences. The Essential Role of Retroviruses in the Evolution of Life in General and Humans in Particular tells the story of how small minute variations or mutations can effect the entire way a species looks acts or even what makes the species. Currently a Professor of Nanoscience at UNCG, Dr. Ethan W. Taylor is a pharmacologist and molecular modeler with 25 years experience studying the structure and pathogenesis of HIV, during which he has gained unique insights into the critical roles of retroviruses and related genomic elements in evolution and human biology. Dr. Taylor’s research work ranges from fundamental contributions to structural bioinformatics and the computer modeling of drugs, DNA and proteins, to discoveries with public health implications, such as his 2010 report with Dr. Lijun Zhao that tobacco smoke increases the infectivity of HIV. Because his research is consistent with a role for certain dietary deficiencies in HIV disease progression, in 2000 he co-founded a nonprofit organization with former US UN Ambassador Andrew Young, with a mission of enhancing the nutritional status of at risk-populations. About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)