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Learn more about Dr. Elisabeth Heath here: https://www.mayoclinic.org/biographie... 1:13 Dr. Heath's opening remarks 4:20 Prostate cancer statistics 7:49 Clinical states model 9:22 Risk stratification and staging workup 11:26 FDA approved agents 13:55 Androgen pathway 15:33 Androgen deprivation side effects 18:09 Overall survival benefit with intensification 20:16 Treatment selection factors 23:00 Clinical considerations 23:43 Disease burden and disease presentation 24:25 Clinical trial updates 25:30 Real-world treatment intensification patterns 26:10 Global data 26:44 Chemotherapy side effects 27:40 Chemotherapy fitness 29:03 Chemotherapy in castrate-resistant disease 29:38 Prostate cancer clinical trial updates 33:10 DNA damage repair pathways 33:40 PARP inhibitors 35:15 PARP inhibitor side effects 36:20 Genetic testing results 37:56 Microsatellite instability-high cancer 38:53 Immunotherapy in prostate cancer 39:28 Sipuleucel-T 41:30 Radium-223 42:26 Radium study and data 43:22 PSMA 49:45 Novel targets in clinical trials 50:16 Dr. Moyad and Dr. Heath Q&A To learn more about prostate cancer, visit http://www.pcri.org Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: https://pcri.org/join Donate to PCRI: https://pcri.org/donate/ Who we are: The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors. #ElisabethHeathMD